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气溶胶气管内定量给药器

来源:本站作者:九游会仪器

详细介绍

大小鼠气溶胶气管内给药套装可输送定量的气溶胶到大鼠、小鼠气管内和肺内,为定量化给药提供了更好的方案:直接对大鼠、小鼠、比格犬、猴子的肺部(气管内)进行定量气溶胶雾化给药给药快捷、操作方便


有三种型号可供选择:大鼠型气管内定量给药套装,小鼠型气管内定量给药套装,大单位气管内定量给药套装


气管内定量给药装置的主要特色:

· 定量 QUANTIFIABLE:将定量的气溶胶给到动物肺部

· 定时 TIMED:可以在一个或多个时间点进行给药

· 有效 EFFECTIVE:气溶胶的吸收效果好,给药快速,效率高,操作方便

· 方便 CONVENIENCE:维护简单,操作方便

 



型号:YAN30012  液体气溶胶肺部给药



型号:YAN30010  干粉气溶胶肺部给药

大小鼠气管内定量给药装置的主要特点:

· 快速精确的直接肺部给药——气溶胶浪费

· 纯机械动力,无外部空气进入;

· 不需加热、推进剂、超声波或压缩空气等,对药物物影响

· 手持式设计,使用非常方便

· 喷射头顶端圆滑的设计,保证安全、温和的插入气管内

· 可高温高压消毒灭菌,可重复使用

· 比其它雾化器和吸入设备提供更高浓度发药物体积或剂量

· 比传统滴注法给药提供更均匀的药物分布


使用方法图例:





另外,可选配大小鼠气管插管喉镜大小鼠气管插管工具包套装、大小鼠气管插管等工具,能更便捷的完成手术。


大鼠、小鼠喉镜



大小鼠气管插管工具包套装


   


气管插管平台(多种款式和型号可选)


     

CG-02M型,适合做小鼠,外尺寸:20*15*20cm 

CG-02R型,适合做大鼠,外尺寸:22*21*28cm

适用于大、小鼠的气管插管手术操作


   

CG-04M型,小鼠型

配合铁架台使用,多角度可调;


   

型号:CG-06M

多角度可调;

大小鼠通用,尺寸约:20*15*15cm



部分参考文献:


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2. Peng, Boya et al. Robust delivery of RIG-I agonists using extracellular vesicles for anti-cancer immunotherapy.Journal of extracellular vesicles vol. 11,4 (2022): e12187. doi:10.1002/jev2.12187

 

3. Wu, Lan et al. Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration.ACS applied materials & interfaces vol. 13,3 (2021): 3722-3737. doi:10.1021/acsami.0c21259

 

4. Tian, Xidong et al. Pulmonary Delivery of Reactive Oxygen Species/Glutathione-Responsive Paclitaxel Dimeric Nanoparticles Improved Therapeutic Indices against Metastatic Lung Cancer.ACS applied materials & interfaces vol. 13,48 (2021): 56858-56872. doi:10.1021/acsami.1c16351

 

5. Gu, Peiyu et al. Protective function of interleukin-22 in pulmonary fibrosis.Clinical and translational medicine vol. 11,8 (2021): e509. doi:10.1002/ctm2.509

 

6. Su, Ruonan et al. Venetoclax nanomedicine alleviates acute lung injury via increasing neutrophil apoptosis.Biomaterials science vol. 9,13 (2021): 4746-4754. doi:10.1039/d1bm00481f

 

7. Yang, Huilin et al. Triptolide dose-dependently improves LPS-induced alveolar hypercoagulation and fibrinolysis inhibition through NF-κB inactivation in ARDS mice.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 139 (2021): 111569. doi:10.1016/j.biopha.2021.111569

 

8. Wu, Yanqi et al. SN50 attenuates alveolar hypercoagulation and fibrinolysis inhibition in acute respiratory distress syndrome mice through inhibiting NF-κB p65 translocation.Respiratory research vol. 21,1 130. 27 May. 2020, doi:10.1186/s12931-020-01372-6

 

9. Han, Meishan et al. Engineering of Stimulus-Responsive Pirfenidone Liposomes for Pulmonary Delivery During Treatment of Idiopathic Pulmonary Fibrosis.Frontiers in pharmacology vol. 13 882678. 25 Apr. 2022, doi:10.3389/fphar.2022.882678

 

10. Wu, Lan et al. Quantitative comparison of three widely-used pulmonary administration methods in vivo with radiolabeled inhalable nanoparticles.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V vol. 152 (2020): 108-115. doi:10.1016/j.ejpb.2020.05.004

 

11. Peng, Jianqing et al. Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration.Molecules (Basel, Switzerland) vol. 27,11 3610. 4 Jun. 2022, doi:10.3390/molecules27113610






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